Neonatal hypoxia and seizures.
نویسندگان
چکیده
2012;33;387 Pediatrics in Review Maria Gillam-Krakauer and Brian S. Carter Neonatal Hypoxia and Seizures http://pedsinreview.aappublications.org/content/33/9/387 located on the World Wide Web at: The online version of this article, along with updated information and services, is http://pedsinreview.aappublications.org/content/suppl/2012/09/05/33.9.387.DC1.html Data Supplement (unedited) at: Pediatrics. All rights reserved. Print ISSN: 0191-9601. Boulevard, Elk Grove Village, Illinois, 60007. Copyright © 2012 by the American Academy of published, and trademarked by the American Academy of Pediatrics, 141 Northwest Point publication, it has been published continuously since 1979. Pediatrics in Review is owned, Pediatrics in Review is the official journal of the American Academy of Pediatrics. A monthly
منابع مشابه
The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants.
OBJECTIVES The objectives of this study were to delineate the etiologic profile and neurodevelopmental outcome of neonatal seizures in the current era of neonatal intensive care and to identify predictors of neurodevelopmental outcome in survivors. METHODS Eighty-nine term infants with clinical neonatal seizures underwent neurologic examination, electroencephalography (EEG), neuroimaging, and...
متن کاملDevelopment of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizures.
PURPOSE To study the development of epilepsy following hypoxia-induced neonatal seizures in Long-Evans rats and to establish the presence of spontaneous seizures in this model of early life seizures. METHODS Long-Evans rat pups were subjected to hypoxia-induced neonatal seizures at postnatal day 10 (P10). Epidural cortical electroencephalography (EEG) and hippocampal depth electrodes were use...
متن کاملIschemic injury suppresses hypoxia-induced electrographic seizures and the background EEG in a rat model of perinatal hypoxic-ischemic encephalopathy.
The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seizures during the 2-h hypoxia treatment, but only HI causes an infarct with seve...
متن کاملبررسی اثر کروسین متعاقب ایجاد مدل صرعی با هیپوکسی بر حافظه احترازی و فعالیت حرکتی در موش صحرایی جوان
Background & Aims: Hypoxia is the most common cause of seizures in the neonatal period. Seizure induced by hypoxia cause permanent increases in excitability of neurons and by changing in activity and synaptic plasticity leads to memory impairment. Crocins (Crocus sativus L.) is a water-soluble carotenoid and is the most important active components of saffron. Most studies indicate that crocin h...
متن کاملDecreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures.
Hypoxic encephalopathy is the most common cause of neonatal seizures and can lead to chronic epilepsy. In rats at postnatal days 10-12 (P10-12), global hypoxia induces spontaneous seizures and chronically decreases seizure threshold, thus mimicking clinical aspects of neonatal hypoxia. We have shown previously that the acute and chronic epileptogenic effects of hypoxia are age-dependent and req...
متن کاملClinical Neonatal Seizures are Independently Associated with Outcome in Infants at Risk for Hypoxic-Ischemic Brain Injury.
OBJECTIVE To examine whether neonatal seizures are associated with neurodevelopmental outcomes in infants with hypoxia-ischemia independent of the presence and severity of brain injury seen on magnetic resonance imaging (MRI). STUDY DESIGN We used multivariate regression to examine the independent effect of clinical neonatal seizures and their treatment on neurodevelopment in 77 term newborns...
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عنوان ژورنال:
- Pediatrics in review
دوره 33 9 شماره
صفحات -
تاریخ انتشار 2012